Szyjka, S.J., Mandal, S., Schoepp, N.G., Tyler, B.M., Yohn, C.B., Poon, Y.S., Villareal, S., Burkart, M.D., Shurin, J.B. & Mayfield, S.P. (2017). Evaluation of phenotype stability and ecological risk of a genetically engineered alga in open pond production. Algal Research 2017, 24 Part A, 378-386

Barajas, J.F., Shakya, G., Moreno, G., Rivera Jr., H., Jackson, D.R., Topper, C.L., Vagstad, A.L., LaClair, J. J., Townsend, C.A., Burkart, M.D., & Tsai, S.C.. (2017). Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Proceedings of the National Academy of Sciences of the United States of America 2017, 114 (21), E4142-E4148

León, B., Kashyap, M., Chan, W., Krug, K., Castro, J., LaClair, J. J., & Burkart, M.D. (2017). A Challenging Pie to Splice: Drugging the Spliceosome. Angewandte Chemie International Edition 2017

Finzel, K., Beld, J., Burkart, M. D., & Charkoudian, L. K. (2017). Utilizing Mechanistic Cross-Linking Technology To Study Protein-Protein Interactions: An Experiment Designed for an Undergraduate Biochemistry Lab. Journal of Chemical Education 2017, 94 (3), pp 375–379.



Mindrebo, J. T., Nartey, C. M., Seto, Y., Burkart, M. D., & Noel, J. P. (2016). Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom. Current Opinion in Structural Biology 2016, Volume 41, 256-257.

Crews, L. A., Balaian, L., Delos Santos, N. P., Leu, H. S., Court, A. C., Lazzari, E., Sadarangani, A., Zipeto, M. A., La Clair, J. J., Villa, R., Kulidjian, A., Storb, R., Morris, S. R., Ball, E. D., Burkart, M. D., & Jamieson, C. H. M. (2016). RNA Splicing Modulation Selectivity Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell 2016, Volume 19, Issue 5, 561-563.

Shurin, J. B., Burkart, M. D. Mayfield, S. P., & Smith, V. H. (2016). Recent Progress and Future Challenges in Algal Biofuel Production. F1000Research 2016, 5 (F1000 Faculty Rev):2434.

Barajas, J. F., Finzel, K., Valentic, T. R., Shakya, G., Gamarra, N., Martinez, D., Meier, J. L., Vagstad, A. L., Newman, A. G., Townsend, C. A., Burkart, M. D. & Tsai, S. C. (2016). Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain. Angewandte Chemie International Edition 201655 13005-13009.

McCulloch, I. P., La Clair, J. J., Jaremko, M. J., & Burkart, M. D. (2016). Fluorescent Mechanism-Based Probe for Aerobic Flavin-Dependent Enzyme Activity. ChemBioChem 2016, 17, 1598-1601.

Kumar, D., Kashyap, M. K., La Clair, J. J., Villa, R., Spaanderman, I., Chien, S., Rassenti, L. Z., Kipps, T. J., Burkart, M. D., & Castro, J. E. (2016). Selectivity in Small Molecule Splicing Modulation. ACS Chemical Biology 2016, 11 (10) 2716-2723

Foley, T. L., Dorjsuren, D., Dexheimer, T. S., Burkart, M. D. Wight, W. C., & Simeonov, A.(2016). A Platform to Enable the Pharmacological Profiling of Small Molecules in Gel-Based Electrophoretic Mobility Shift Assays. Journal of Biomolecular Screening 2016, vol. 21(10) 1125-1131.

Koo, H. J., Vickery, C. R., Xu, Y., Louie, G. V., O'Maille, P. E., Bowman, M., Nartey, C. M., Burkart, M. D. & Noel, J. P. (2016). Biosynthetic potential of sesquiterpene synthases: Product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. The Journal of Antibiotics 2016, 69, 524-533.

Uranga, C. C., Beld, J., Mrse, A., Córdova-Guerrero, I., Burkart, M. D. & Hernández-Martínez, R. (2016). Data from mass spectrometry, NMR spectra, GC-MS of fatty acid esters produced by Lasiodiplodia theobromae. Data in Brief 2016, 8, 31-39.

Uranga, C. C., Beld, J., Mrse, A., Córdova-Guerrero, I., Burkart, M. D. & Hernández-Martínez, R. (2016). Fatty acid esters produced by Lasiodiplodia theobromae function as growth regulators in tobacco seedlings. Biochemical and Biophysical Research Communications 2016, 472, 339-345.

Finkel, K., & Burkart, M. D. (2016). Traffic Control in Modular Polyketide Synthases. ACS Central Science 2016, 2 (1), 9-11.

Dhar, S., La Clair, J.J., León, B., Hammons, J.C., Yu, Z., Kashyap, M.K., Castro, J.E. and Burkart, M.D. (2016). A Carbohydrate-Derived Splice Modulator. Journal of the American Chemical Society 2016, 138 (15), pp 5063–5068.

Rivera, H., Dhar, S., La Clair, J. J., Tsai, S. C., & Burkart, M. D. (2016). An unusual intramolecular trans-amidationTetrahedron 2016.

Tallorin, L., Finzel, K., Nguyen, Q. G., Beld, J., La Clair, J. J., & Burkart, M. D. (2016). Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction. Journal of the American Chemical Society 2016138(12), 3962-3965.

Beld, J., Abbriano, R., Finzel, K., Hildebrand, M., & Burkart, M. D. (2016). Probing fatty acid metabolism in bacteria, cyanobacteria, green microalgae and diatoms with natural and unnatural fatty acids. Molecular BioSystems 2016,12(4), 1299-1312.

Patterson, J.P., Collins, D.B., Michaud, J.M., Axson, J.L., Sultana, C.M., Moser, T., Dommer, A.C., Conner, J., Grassian, V.H., Stokes, M.D. and Deane, G.B. (2016). Sea Spray Aerosol Structure and Composition Using Cryogenic Transmission Electron Microscopy. ACS Central Science 2016, 2 (1), pp 40–47.

Vickery, C. R., La Clair, J. J., Burkart, M. D., & Noel, J. P. (2016). Harvesting the biosynthetic machineries that cultivate a variety of indispensable plant natural products. Current opinion in chemical biology 201631, 66-73.



Moynié, L., Hope, A.G., Finzel, K., Schmidberger, J., Leckie, S.M., Schneider, G., Burkart, M.D., Smith, A.D., Gray, D.W. and Naismith, J.H.(2015). A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA. Journal of molecular biology 2015.

Finzel, K., Nguyen, C., Jackson, D. R., Gupta, A., Tsai, S. C., & Burkart, M. D. (2015). Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA. Chemistry & biology 201522(11), 1453-1460.

Jaremko, M. J., Lee, D. J., Opella, S. J., & Burkart, M. D. (2015). Structure and substrate sequestration in the pyoluteorin type II peptidyl carrier protein PltL. Journal of the American Chemical Society 2015137(36), 11546-11549.

Lin, L., Nonejuie, P., Munguia, J., Hollands, A., Olson, J., Dam, Q., Kumaraswamy, M., Rivera, H., Corriden, R., Rohde, M., Hensler, M.E., Burkart, M.D., Pogliano, J., Sakoulas, G., Nizet, V. (2015). Azithromycin synergizes with cationic antimicrobial peptides to exert bactericidal and therapeutic activity against highly multidrug-resistant gram-negative bacterial pathogens. EBioMedicine 20152(7), 688-696.

Cahill, J. F., Darlington, T. K., Fitzgerald, C., Schoepp, N. G., Beld, J., Burkart, M. D., & Prather, K. A. (2015). Online Analysis of Single Cyanobacteria and Algae Cells under Nitrogen-Limited Conditions Using Aerosol Time-of-Flight Mass Spectrometry. Analytical chemistry 201587(16), 8039-8046.

Ferreira-Camargo, L. S., Tran, M., Beld, J., Burkart, M. D., & Mayfield, S. P. (2015). Selenocystamine improves protein accumulation in chloroplasts of eukaryotic green algae. AMB Express 20155(1), 1-11.

Kashyap, M.K., Kumar, D., Villa, R., La Clair, J.J., Benner, C., Sasik, R., Jones, H., Ghia, E.M., Rassenti, L.Z., Kipps, T.J. and Burkart, M.D. (2015). Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. haematologica, Haematologica 2015, 100(7), 945-954.

Konno, S., Ishikawa, F., Suzuki, T., Dohmae, N., Burkart, M. D., & Kakeya, H. (2015). Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases. Chemical Communications201551(12), 2262-2265.

Finzel, K., Lee, D. J., & Burkart, M. D. (2015). Using Modern Tools To Probe the Structure–Function Relationship of Fatty Acid Synthases.ChemBioChem 201516(4), 528-547.

Beld, J., Lee, D. J., & Burkart, M. D. (2015). Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Molecular BioSystems 201511(1), 38-59.

Tallorin, L., Lindert, S., Nguyen, Q. G., Burkart, M. D., & McCammon, J. A. (2015). In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors. Journal of computer-aided molecular design 201529(1), 79-87.



Ku, T. H., Sahu, S., Kosa, N. M., Pham, K. M., Burkart, M. D., & Gianneschi, N. C. (2014). Tapping a Bacterial Enzymatic Pathway for the Preparation and Manipulation of Synthetic Nanomaterials. Journal of the American Chemical Society 2014, 136(50), 17378-17381

Shakya G, Rivera H Jr, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, Burkart MD. (2014). Modeling Linear and Cyclic PKS Intermediates through Atom Replacement. Journal of the American Chemical Society 2014,136(48), 16792-16799.

Beld, J., Cang, H., & Burkart, M. D. (2014). Visualizing the Chain‐Flipping Mechanism in Fatty‐Acid Biosynthesis. Angewandte Chemie International Edition 201453(52), 14456-14461.

Beld, J., Finzel, K., & Burkart, M. D. (2014). Versatility of Acyl-Acyl Carrier Protein Synthetases. Chemistry & biology 201421(10), 1293-1299.

Tallorin, L., Durrant, J. D., Nguyen, Q. G., McCammon, J. A., & Burkart, M. D. (2014). Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase. Bioorganic & medicinal chemistry 201422(21), 6053-6061.

Beld, J., Blatti, J. L., Behnke, C., Mendez, M., & Burkart, M. D. (2014). Evolution of acyl-ACP thioesterases and β-ketoacyl-ACP synthases revealed by protein–protein interactions. Journal of applied phycology 201426(4), 1619-1629.

Schoepp, N. G., Stewart, R. L., Sun, V., Quigley, A. J., Mendola, D., Mayfield, S. P., & Burkart, M. D. (2014). System and Method for Research-Scale Outdoor Production of Microalgae and CyanobacteriaBioresource Technology 2014, 166, 273-281

Bruegger, J., Caldara, G., Beld, J., Burkart, M. D., & Tsai, S. C. S. (2014). 12 Polyketide Synthase: Sequence, Structure, and FunctionNatural Products: Discourse, Diversity, and Design 2014, 219.

Vickery, C. R., Kosa, N. M., Casavant, E. P., Duan, S., Noel, J. P., & Burkart, M. D. (2014). Structure, biochemistry, and inhibition of essential 4´-phosphopantetheinyl transferases from two species of Mycobacteria. ACS Chemical Biology 2014, 9(9), 1939-1944

Rothmann, M., Kosa, N., & Burkart, M. (2014). Resin Supported Acyl Carrier Protein Labeling StrategiesRSC Advances 2014, 4(18), 9092-9097.

Foley, T. L., Rai, G., Yasgar, A., Daniel, T., Baker, H. L., Attene-Ramos, M., Kosa, N.M., Leister, W., Burkart, M.D., Jadhav, Y., Simeonov, A. and Maloney, D. J. (2014). 4-(3-Chloro-5-(trifluoromethyl) pyridin-2-yl)-N-(4-methoxypyridin-2-yl) piperazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial GrowthJournal of medicinal chemistry 2014.

Kosa, N. M., Pham, K. M., & Burkart, M. D. (2014). Chemoenzymatic exchange of phosphopantetheine on protein and peptideChemical Science 2014, 5(3), 1179-1186

Beld, J., Sonnenschein, E. C., Vickery, C. R., Noel, J. P., & Burkart, M. D. (2014). The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life. Natural product reports 201431(1), 61-108.

Kosa, N. M., Foley, T. L., & Burkart, M. D. (2014). Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors.The Journal of antibiotics 201467(1), 113-120.

Nguyen, C., Haushalter, R. W., Lee, D. J., Markwick, P. R., Bruegger, J., Caldara-Festin, G., Finzel, K., Jackson. D.R., Ishikawa, F., O'Dowd, B., McGammon, A., Opella, S.J., Tsai, S.-C. & Burkart, M. D. (2013). Trapping the dynamic acyl carrier protein in fatty acid biosynthesisNature 2014, 505(7483), 427-431



Crews, L. A., Zipeto, M., Anna, K., Ball, E. D., Burkart, M. D., & Jamieson, C. H. (2013). A Highly Selective SF3B1-Targeted Splicing Inhibitor Reduces Human CD34+ Cell Survival and Self-Renewal In Acute Myeloid Leukemia.Blood 2013122(21), 1653-1653.

Beld, J., Blatti, J. L., Behnke, C., Mendez, M., & Burkart, M. D. (2013). Evolution of acyl-ACP thioesterases and β-ketoacyl-ACP synthases revealed by protein–protein interactions. Journal of Applied Phycology 2013, 1-11.

Javidpour, P., Bruegger, J., Srithahan, S., Korman, T. P., Crump, M. P., Crosby, J., Burkart, M.D., Tsai, S. C. (2013). The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase. Chemistry & biology 201320(10), 1225-1234.

Bruegger, J., Haushalter, B., Vagstad, A., Shakya, G., Mih, N., Townsend, C. A., Burkart, M.D., Tsai, S. C.,(2013). Probing the Selectivity and Protein⋅ Protein Interactions of a Nonreducing Fungal Polyketide Synthase Using Mechanism-Based Crosslinkers. Chemistry & biology 201320(9), 1135-1146.

Villa, R., Kashyap, M. K., Kumar, D., Kipps, T. J., Castro, J. E., La Clair, J. J., & Burkart, M. D. (2013). Stabilized cyclopropane analogs of the splicing inhibitor FD-895Journal of medicinal chemistry 201356(17), 6576-6582.

Thomsen, M., Vogensen, S. B., Buchardt, J., Burkart, M. D., & Clausen, R. P. (2013). Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogsOrg. Biomol. Chem 2013.11(43), 7606-7610.

Ishikawa, F., Haushalter, R. W., Lee, D. J., Finzel, K., & Burkart, M. D. (2013). Sulfonyl 3-alkynyl pantetheinamides as mechanism-based crosslinkers of ACP dehydratase. Journal of the American Chemical Society 2013, 135 (24), 8846-8849.

Stewart Jr, C., Vickery, C. R., Burkart, M. D., & Noel, J. P. (2013). Confluence of structural and chemical biology: plant polyketide synthases as biocatalysts for a bio-based future. Current opinion in plant biology 2013, 16 (3), 365-372.

Yu, W. L., Jones, B. D., Kang, M., Hammons, J. C., La Clair, J. J., & Burkart, M. D. (2013). Spirohexenolide A Targets Human Macrophage Migration Inhibitory Factor (hMIF). Journal of natural products 2013,76 (5), 817-823.

Burkart, M. D., & Mayfield, S. P.. Biofuels for the 21st century. Current opinion in chemical biology 2013.

Blatti, J. L., Michaud, J., & Burkart, M. D. (2013). Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Current opinion in chemical biology 2013, 17 (3), 496-505.

Rothmann, M., Kang, M., Villa, R., Ntai, I., La Clair, J. J., Kelleher, N. L., Chapman, E. & Burkart, M. D. Metabolic Perturbation of an Essential Pathway: Evaluation of a Glycine Precursor of Coenzyme A. Journal of the American Chemical Society 2013, 135(16), 5962-5965.

Lipson, J. M., Thomsen, M., Moore, B. S., Clausen, R. P., La Clair, J. J., & Burkart, M. D. A Tandem Chemoenzymatic Methylation by S-Adenosyl-L-methionine. ChemBioChem 2013, 14(8), 950-953.



Hur, G. H., Vickery, C. R., & Burkart, M. D.. Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology. Natural product reports 2012, 29(10), 1074-1098.

Villa, R.; Mandel, A.L.,; Jones, B.D.; La Clair, J.J.; Burkart, M.D. Structure of FD-895 Revealed through Total Synthesis Organic Letters 2012, doi 10.1021/ol3023006

Kosa, N.M., Haushalter, R.W., Smith, A.R., Burkart, M.D., Reversible labeling of native and fusion-protein motif, Nature Methods 2012, 9 (10), 981-984

Blatti, J.L., Beld, J., Behnke, C.A., Mendez, M., Mayfield, S.P., Burkart, M.D., Manipulating Fatty Acid Biosynthesis in Microalgae for Biofuel through Protein-Protein Interactions. PLoS One 2012, 9, e42949

Van Der Westhuyzen, R.; Hammons, J. C.; Meier, J. L.; Dahesh, S.; Moolman, W. J. A.; Pelly, S. C.; Nizet, V.; Burkart, M. D.; Strauss, E., The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chemistry and Biology 2012, 19 (5), 559-571

Blatti, J. L.; Burkart, M. D., Releasing stored solar energy within pond scum: Biodiesel from algal lipids. Journal of Chemical Education 2012, 89 (2), 239-242

Ishikawa, F.; Haushalter, R. W.; Burkart, M. D., Dehydratase-specific probes for fatty acid and polyketide synthases. Journal of the American Chemical Society 2012, 134 (2), 769-772

Rothmann, M.; Niessen, S.; Haushalter, R. W.; Cravatt, B. F.; Burkart, M. D., Resin-based investigation of acyl carrier protein interaction networks in Escherichia coli. Bioorganic and Medicinal Chemistry 2012, 20 (2), 667-671



La Clair, J. J.; Rheingold, A. L.; Burkart, M. D., Ganodone, a bioactive benzofuran from the fruiting bodies of Ganoderma tsugae. Journal of Natural Products 2011, 74 (10), 2045-2051

Jones, A. C.; Monroe, E. A.; Podell, S.; Hess, W. R.; Klages, S.; Esquenazi, E.; Niessen, S.; Hoover, H.; Rothmann, M.; Lasken, R. S.; Yates Iii, J. R.; Reinhardt, R.; Kube, M.; Burkart, M. D.; Allen, E. E.; Dorrestein, P. C.; Gerwick, W. H.; Gerwick, L., Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America 2011, 108 (21), 8815-8820

Yu, W. L.; Ansari, W.; Schoepp, N. G.; Hannon, M. J.; Mayfield, S. P.; Burkart, M. D., Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microbial Cell Factories 2011, 10.

Haushalter, R.W., Filipp, F.V., Ko, K.-S., Yu, R., Opella, S.J., Burkart, M.D., Binding and pK a modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. ACS Chemical Biology 2010, 6 (5), pp. 413-418

Worthington, A.S., Hur, G.H., Burkart, M.D., Activity-guided engineering of natural product carrier proteins. Molecular BioSystems 2011, 7 (2), pp. 365-370

Meier, J.L., Burkart, M.D., Proteomic analysis of polyketide and nonribosomal peptide biosynthesis. Current Opinion in Chemical Biology 2011, 15 (1), pp. 48-56

Meier, J.L., Patel, A.D., Niessen, S., Meehan, M., Kersten, R., Yang, J.Y., Rothmann, M., Cravatt, B.F., Dorrestein, P.C., Burkart, M.D., Bafna, V., Practical 4′-Phosphopantetheine active site discovery from proteomic samples. Journal of Proteome Research 2011, 10 (1), pp. 320-329



Reyes, C.P., Clair, J.J.L., Burkart, M.D., Metabolic probes for imaging endosymbiotic bacteria within toxic dinoflagellates. Chemical Communications 2010, 46 (43), pp. 8151-8153

Ko, K.-S., Alexander, M.D., Fontaine, S.D., Biggs-Houck, J.E., La Clair, J.J., Burkart, M.D., Synthetic studies on the mycolactone core. Organic and Biomolecular Chemistry 2010, 8 (22), pp. 5159-5165

Yu, W.-L., Guizzunti, G., Foley, T.L., Burkart, M.D., La Clair, J.J., An optimized immunoaffinity fluorescent method for natural product target elucidation. Journal of Natural Products 2010, 73 (10), pp. 1659-1666

Foley, T.L., Yasgar, A., Garcia, C.J., Jadhav, A., Simeonov, A., Burkart, M.D., Preparation of FRET reporters to support chemical probe development. Organic and Biomolecular Chemistry 2010, 8 (20), pp. 4601-4606

Jones, B.D., La Clair, J.J., Moore, C.E., Rheingold, A.L., Burkart, M.D., Convergent route to the spirohexenolide macrocycle. Organic Letters 2010, 12 (20), pp. 4516-4519

Meier, J.L., Haushalter, R.W., Burkart, M.D., A mechanism based protein crosslinker for acyl carrier protein dehydratases. Bioorganic and Medicinal Chemistry Letters 2010, 20 (16), pp. 4936-4939

Worthington, A.S., Porter, D.F., Burkart, M.D., Mechanism-based crosslinking as a gauge for functional interaction of modular synthases. Organic and Biomolecular Chemistry 2010, 8 (8), pp. 1769-1772

Yasgar, A.; Foley, T. L.; Jadhav, A.; Inglese, J.; Burkart, M. D.; Simeonov, A., A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular BioSystems 2010, 6, 365-375



Kang, M.; Jones, B. D.; Mandel, A. L.; Hammons, J. C.; DiPasquale, A. G.; Rheingold, A. L.; La Clair, J. J.; Burkart, M. D., Isolation, structure elucidation, and antitumor activity of spirohexenolides A and B. Journal of Organic Chemistry 2009, 74 (23), 9054-9061

Lear, M. J.; Simon, O.; Foley, T. L.; Burkart, M. D.; Baiga, T. J.; Noel, J. P.; DiPasquale, A. G.; Rheingold, A. L.; La Clair, J. J., Laetirobin from the parasitic growth of Laetiporus sulphureus on Robinia pseudoacacia. Journal of Natural Products 2009, 72 (11), 1980-1987

Meier, J. L.; Niessen, S.; Hoover, H. S.; Foley, T. L.; Cravatt, B. F.; Burkart, M. D., An Orthogonal Active Site Identification System (OASIS) for proteomic profiling of natural product biosynthesis. ACS Chemical Biology 2009, 4 (11), 948-957

Najmabadi, P.; Lee, H. H.; Aung, T.; Thuya, A.; Ng, J.; La Clair, J. J.; Burkart, M. D., Grafta: A 3D environment for biomolecular networks. International Journal of Bioinformatics Research and Applications 2009, 5 (5), 564-569

Mercer, A. C.; Meier, J. L.; Torpey, J. W.; Burkart, M. D., In vivo modification of native carrier protein domains. ChemBioChem 2009, 10 (6), 1091-1100

Meier, J. L.; Burkart, M. D., Chapter 9 Synthetic Probes for Polyketide and Nonribosomal Peptide Biosynthetic Enzymes. Methods in Enzymology 2009; Vol. 458, pp 219-254

Meier, J. L.; Burkart, M. D., The chemical biology of modular biosynthetic enzymes. Chemical Society Reviews 2009, 38 (7), 2012-2045

Hur, G. H.; Meier, J. L.; Baskin, J.; Codelli, J. A.; Bertozzi, C. R.; Marahiel, M. A.; Burkart, M. D., Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis. Chemistry and Biology 2009, 16 (4), 372-381

Foley, T. L.; Young, B. S.; Burkart, M. D., Phosphopantetheinyl transferase inhibition and secondary metabolism. FEBS Journal 2009, 276 (23), 7134-7145

Foley, T. L.; Burkart, M. D., A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Analytical Biochemistry 2009, 394 (1), 39-47



Worthington, A. S.; Hur, G. H.; Meier, J. L.; Cheng, Q.; Moore, B. S.; Burkart, M. D., Probing the compatibility of type II ketosynthase-carrier protein partners. ChemBioChem 2008, 9 (13), 2096-2103

Najmabadi, P.; Ko, K. S.; La Clair, J. J.; Burkart, M. D., A Method for Fabrication of Polycarbonate-Based Bioactive Platforms. JALA - Journal of the Association for Laboratory Automation 2008, 13 (5), 284-288

Mercer, A. C.; Meier, J. L.; Hur, G. H.; Smith, A. R.; Burkart, M. D., Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli. Bioorganic and Medicinal Chemistry Letters 2008, 18 (22), 5991-5994

Meier, J. L.; Mercer, A. C.; Burkart, M. D., Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. Journal of the American Chemical Society 2008, 130 (16), 5443-5445

Meier, J. L.; Barrows-Yano, T.; Foley, T. L.; Wike, C. L.; Burkart, M. D., The unusual macrocycle forming thioesterase of mycolactone. Molecular BioSystems 2008, 4 (6), 663-671

Kapur, S.; Worthington, A.; Tang, Y.; Cane, D. E.; Burkart, M. D.; Khosla, C., Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase. Bioorganic and Medicinal Chemistry Letters 2008, 18 (10), 3034-3038

Haushalter, R. W.; Worthington, A. S.; Hur, G. H.; Burkart, M. D., An orthogonal purification strategy for isolating crosslinked domains of modular synthases. Bioorganic and Medicinal Chemistry Letters 2008, 18 (10), 3039-3042

Ko KS, Najmabadi P, La Clair JJ, Burkart MD. Affinity Analyses on Moldable Optical Polycarbonate. Chembiochem. 2008, 9, 201-205.



Mandel AL, Jones BD, La Clair JJ, Burkart MD. A synthetic entry to pladienolide B and FD-895. Bioorg Med Chem Lett. 2007,17, 5159-5164.

Mercer AC, Burkart MD. The ubiquitous carrier protein—a window to metabolite biosynthesis. Nat. Prod. Rep. 2007, 24, 750-773.

Worthington AS, Burkart MD. The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis. ACS Chem Biol. 2007, 2, 152-154.

Najmabadi P, La Clair JJ, Burkart MD. A systems perspective to digital structures in molecular analysis. Org Biomol Chem. 2007, 5, 214-222.

Foley TL, Burkart MD. Site-specific protein modification: advances and applications. Curr Opin Chem Biol. 2007, 11, 12-19.



Worthington AS, Rivera H, Torpey JW, Alexander MD, Burkart MD. Mechanism based protein crosslinking probes to investigate carrier protein mediated synthesis. ACS Chemical Biology 2006, 1, 687-691.

Alexander, Matthew D., Fontaine, Shaun D., La Clair, James J., DiPasquale, Antonio G., Rheingold, Arnold L., Burkart, Michael D. Synthesis of the mycolactone core by ring-closing metathesis. Chemical Communications 2006, 44, 4602 - 4604.

Mercer, Andrew C.; Burkart, Michael D.. Chemical expansion of cofactor activity. Nature Chemical Biology 2006, 2, 8-10.

La Clair JJ, Burkart MD. Geometry in digital molecular arrays. Org Biomol Chem. 2006, 4, 3052-3055.

Meier, Jordan L.; Mercer, Andrew C.; Rivera, Heriberto, Jr.; Burkart, Michael D. Synthesis and Evaluation of Bioorthogonal Pantetheine Analogues for in Vivo Protein Modification. Journal of the American Chemical Society 2006, 128, 12174-12184.

Worthington, Andrew S.; Burkart, Michael D. One-pot chemo-enzymatic synthesis of reporter-modified proteins. Organic & Biomolecular Chemistry 2006, 4, 44-46.

Mercer, Andrew C.; Burkart, Michael D. Enzyme-Assisted Antibiotic Engineering- the Wright Way. Chemistry & Biology 2005, 12, 147-148.

Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjug Chem. 2005, 16, 1352-1355.

Mercer, Andrew C.; La Clair, James J.; Burkart, Michael D.. Fluorescent multiplex analysis of carrier protein post-translational modification. ChemBioChem 2005, 6, 1335-1337.

Clarke KM, La Clair JJ, Burkart MD. A three-component photoreversible tag for thiols. J Org Chem. 2005, 70, 3709-3711.

Clarke, Kristine M.; Mercer, Andrew C.; La Clair, James J.; Burkart, Michael D.. In Vivo Reporter Labeling of Proteins via Metabolic Delivery of Coenzyme A Analogues. Journal of the American Chemical Society 2005, 127, 11234-11235.

Mandel, Alexander L.; La Clair, James J.; Burkart, Michael D.. Modular Synthesis of Pantetheine and Phosphopantetheine. Organic Letters 2004, 6, 4801-4803.

La Clair, James J.; Foley, Timothy L.; Schegg, Tracy R.; Regan, Conor M.; Burkart, Michael D.. Manipulation of Carrier Proteins in Antibiotic Biosynthesis. Chemistry & Biology 2004, 11, 195-201

Burkart, Michael D. Metabolic engineering-a genetic toolbox for small molecule organic synthesis. Organic & Biomolecular Chemistry 2003, 1, 1-4.

La Clair JJ, Burkart MD. Molecular screening on a compact disc. Org Biomol Chem. 2003, 1, 3244-329.